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Opinion|Videos|March 6, 2025

Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

This segment explores the use of stereotactic body radiation therapy (SBRT) for treating small peripheral lesions in patients with lymph node–positive cancer, compared with conventional intensity-modulated radiation therapy. It discusses the potential advantages of SBRT in reducing treatment duration, its theoretical biological effects, and ongoing studies like the LU008 phase 3 trial.

Episodes in this series

EP. 1 Defining Resectability in Stage III NSCLC: Addressing Key Controversies

EP. 1 Defining Resectability in Stage III NSCLC: Addressing Key Controversies

EP. 2 Multidisciplinary Strategies for Optimizing Care in Unresectable Stage III NSCLC

EP. 2 Multidisciplinary Strategies for Optimizing Care in Unresectable Stage III NSCLC

EP. 3 Optimizing Biomarker Testing for Unresectable Stage III NSCLC

EP. 3 Optimizing Biomarker Testing for Unresectable Stage III NSCLC

EP. 4 Overcoming Barriers to Biomarker Testing in Unresectable NSCLC: Strategies for Improved Access and Implementation

EP. 4 Overcoming Barriers to Biomarker Testing in Unresectable NSCLC: Strategies for Improved Access and Implementation

EP. 5 Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

EP. 5 Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

EP. 6 Consolidation Durvalumab in Unresectable Stage III NSCLC: Management Strategies and the Role of ctDNA

EP. 6 Consolidation Durvalumab in Unresectable Stage III NSCLC: Management Strategies and the Role of ctDNA

EP. 7 Assessment and Management Strategies for Pneumonitis in Durvalumab Consolidation Post Chemoradiotherapy

EP. 7 Assessment and Management Strategies for Pneumonitis in Durvalumab Consolidation Post Chemoradiotherapy

EP. 8 Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

EP. 8 Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

EP. 9 A 76-Year-Old Woman With Locally Advanced Unresectable Stage III EGFRm NSCLC

EP. 9 A 76-Year-Old Woman With Locally Advanced Unresectable Stage III EGFRm NSCLC

EP. 10 Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

EP. 10 Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

EP. 11 Key Takeaways From the PACIFIC-2 Trial: The Role of Concurrent Immunotherapy With CRT

EP. 11 Key Takeaways From the PACIFIC-2 Trial: The Role of Concurrent Immunotherapy With CRT

EP. 12 Closing Thoughts and Clinical Pearls: Future Perspectives in NSCLC

EP. 12 Closing Thoughts and Clinical Pearls: Future Perspectives in NSCLC

Video content above is prompted by the following:

Can you discuss the potential role of SBRT in unresectable non–small cell lung cancer (NSCLC) and any trials that can help guide decisions?

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