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Opinion|Videos|March 6, 2025

Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

This segment transitions to discussing the management of unresectable non–small cell lung cancer (NSCLC), focusing on the distinctions between concurrent and sequential chemoradiation. It highlights patient selection, treatment tolerability, the role of advanced radiation technologies, and considerations for minimizing adverse effects while ensuring optimal outcomes.

Episodes in this series

EP. 1 Defining Resectability in Stage III NSCLC: Addressing Key Controversies

EP. 1 Defining Resectability in Stage III NSCLC: Addressing Key Controversies

EP. 2 Multidisciplinary Strategies for Optimizing Care in Unresectable Stage III NSCLC

EP. 2 Multidisciplinary Strategies for Optimizing Care in Unresectable Stage III NSCLC

EP. 3 Optimizing Biomarker Testing for Unresectable Stage III NSCLC

EP. 3 Optimizing Biomarker Testing for Unresectable Stage III NSCLC

EP. 4 Overcoming Barriers to Biomarker Testing in Unresectable NSCLC: Strategies for Improved Access and Implementation

EP. 4 Overcoming Barriers to Biomarker Testing in Unresectable NSCLC: Strategies for Improved Access and Implementation

EP. 5 Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

EP. 5 Tailoring Chemoradiotherapy Approaches in Unresectable Stage III NSCLC

EP. 6 Consolidation Durvalumab in Unresectable Stage III NSCLC: Management Strategies and the Role of ctDNA

EP. 6 Consolidation Durvalumab in Unresectable Stage III NSCLC: Management Strategies and the Role of ctDNA

EP. 7 Assessment and Management Strategies for Pneumonitis in Durvalumab Consolidation Post Chemoradiotherapy

EP. 7 Assessment and Management Strategies for Pneumonitis in Durvalumab Consolidation Post Chemoradiotherapy

EP. 8 Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

EP. 8 Exploring the Role of SBRT in Unresectable NSCLC: Patient Selection and Trial Insights

EP. 9 A 76-Year-Old Woman With Locally Advanced Unresectable Stage III EGFRm NSCLC

EP. 9 A 76-Year-Old Woman With Locally Advanced Unresectable Stage III EGFRm NSCLC

EP. 10 Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

EP. 10 Expert Insights on the LAURA Trial: Osimertinib After CRT in Unresectable Stage III EGFRm NSCLC as a New Standard of Care

EP. 11 Key Takeaways From the PACIFIC-2 Trial: The Role of Concurrent Immunotherapy With CRT

EP. 11 Key Takeaways From the PACIFIC-2 Trial: The Role of Concurrent Immunotherapy With CRT

EP. 12 Closing Thoughts and Clinical Pearls: Future Perspectives in NSCLC

EP. 12 Closing Thoughts and Clinical Pearls: Future Perspectives in NSCLC

Video content above is prompted by the following:

How do you select patients with unresectable stage 3 NSCLC for sequential vs concurrent chemoradiotherapy (cCRT)? How do available data help inform your treatment decision?
PACIFIC: 5-year follow-up data
PACIFIC-R
PACIFIC-6
How do you manage patients not suitable for cCRT?

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