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Opinion|Videos|September 4, 2024

Expert Insights: SG Adverse Events Management including Alopecia & Nausea

Author(s)Hope S. Rugo, MD, FASCO, Aditya Bardia, MD, MPH, FASCO

Panelists discuss how to manage side effects of sacituzumab govitecan (SG), including counseling on alopecia, proactive management strategies, routine antiemetic premedications, and adjustments for chemotherapy-induced nausea and vomiting, as well as recommended breakthrough antinausea medications for home use.

Episodes in this series

EP. 1 Overview of Current ADCs in Breast Cancer

EP. 1 Overview of Current ADCs in Breast Cancer

EP. 2 ADCs in Breast Cancer: Mechanism of Action, and Components

EP. 2 ADCs in Breast Cancer: Mechanism of Action, and Components

EP. 3 Overview of SG-Related Neutropenia Rates in Real-Life Setting and in Clinical Trials

EP. 3 Overview of SG-Related Neutropenia Rates in Real-Life Setting and in Clinical Trials

EP. 4 Expert Perspectives on the Management of SG-Related Neutropenia

EP. 4 Expert Perspectives on the Management of SG-Related Neutropenia

EP. 5 Navigating SG-related Diarrhea

EP. 5 Navigating SG-related Diarrhea

EP. 6 Expert Insights: SG Adverse Events Management including Alopecia & Nausea

EP. 6 Expert Insights: SG Adverse Events Management including Alopecia & Nausea

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 7 Overview of Cardiotoxicity Risk with T-DXd and Monitoring Strategies along with Anti-Nausea strategies

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 8 Clinical Management Considerations: Pneumonitis associated with T-DXd

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 9 Expert Perspectives: T-DM1 Adverse Events Overview and Management Strategies

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 10 Role of Multidisciplinary Team in the Management of Patients Receiving ADCs in Breast Cancer

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 11 Future Perspectives on ADCs in Breast Cancer

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 12 Expert Insights: Investigational ADCs Safety Profiles

Hope Rugo, MD, FASCO, and Aditya Bardia, MD, MPH, FASCO

EP. 13 Key Takeaways and Clinical Practice Pearls in the Treatment of Patients with Breast Cancer Receiving ADCs

Video content above is prompted by the following:

Aside from neutropenia and diarrhea, we may also see alopecia and nausea with sacituzumab govitecan (SG)….
What do you counsel your patients regarding the alopecia associated with SG? Are there any proactive management strategies?
Please comment on your routine antiemetics premedications for SG.
If your patient experiences chemotherapy-induced nausea and vomiting with their first infusion of SG on Day 1, how do you typically manage their antinausea meds for Day 8 infusion?
What breakthrough antinausea medications do you generally prescribe for patients to have at home?

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