Opinion|Videos|December 23, 2025
Factors Shaping Second-Line BTK Inhibitor Decisions in R/R Mantle Cell Lymphoma
Author(s)Luhua (Michael) Wang, MD, Nakhle Saba, MD
Michael Wang, MD, and Nakhle Saba, MD, discuss factors that drive BTK inhibitor selection in second-line mantle cell lymphoma.
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Michael Wang, MD, and Nakhle Saba, MD, discuss key factors that guide BTK inhibitor selection in the second-line setting for relapsed/refractory mantle cell lymphoma. They examine how prior therapy, toxicity profiles, comorbidities, and disease biology affect treatment choice. Wang and Saba emphasize the importance of individualized decision-making when sequencing BTK inhibitors.
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