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Opinion|Videos|April 21, 2025

Looking Into the Future and at Unmet Needs in EGFRm NSCLC

Author(s)Christine M. Lovly, MD, PhD, Balazs Halmos, MD, MS

Panelists discuss how medical professionals identify key unmet needs in EGFR-mutated non–small cell lung cancer (NSCLC) treatment, particularly in overcoming resistance. Challenges include addressing acquired resistance to targeted therapies, enhancing central nervous system penetration, managing toxicity, and developing novel agents or combinations to improve long-term outcomes.

Episodes in this series

2 experts in this video

EP. 1 Brief Overview of the Treatment Landscape of First-Line EGFRm NSCLC

2 experts in this video

EP. 2 FLAURA, FLAURA2, and MARIPOSA: Key Takeaways to Impact First-Line Treatment Approach

2 experts in this video

EP. 3 Clinical Factors to Consider When Choosing a Treatment Strategy

2 experts in this video

EP. 4 Treatment Strategies to Manage AEs in EGFRm NSCLC

2 experts in this video

EP. 5 The Multidisciplinary Team’s Role in EGFRm NSCLC Management

2 experts in this video

EP. 6 Role of Rebiopsy at Disease Progression in EGFRm NSCLC

2 experts in this video

EP. 7 Treatment Sequencing in Disease Progression in EGFRm NSCLC

2 experts in this video

EP. 8 Looking Into the Future and at Unmet Needs in EGFRm NSCLC

Video content above is prompted by the following:

What do you see as the biggest unmet needs in EGFR-mutated NSCLC treatment, particularly in the resistance setting?

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