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Opinion|Videos|April 7, 2025

Clinical Factors to Consider When Choosing a Treatment Strategy

Author(s)Christine M. Lovly, MD, PhD, Balazs Halmos, MD, MS

Panelists discuss how medical professionals assess patient characteristics such as molecular profile, disease burden, and central nervous system (CNS) involvement to tailor treatment. Monotherapy may be favored for lower burden or specific mutations, whereas combination therapy is chosen for aggressive disease or resistance risk.

Episodes in this series

2 experts in this video

EP. 1 Brief Overview of the Treatment Landscape of First-Line EGFRm NSCLC

2 experts in this video

EP. 2 FLAURA, FLAURA2, and MARIPOSA: Key Takeaways to Impact First-Line Treatment Approach

2 experts in this video

EP. 3 Clinical Factors to Consider When Choosing a Treatment Strategy

2 experts in this video

EP. 4 Treatment Strategies to Manage AEs in EGFRm NSCLC

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EP. 5 The Multidisciplinary Team’s Role in EGFRm NSCLC Management

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EP. 6 Role of Rebiopsy at Disease Progression in EGFRm NSCLC

2 experts in this video

EP. 7 Treatment Sequencing in Disease Progression in EGFRm NSCLC

2 experts in this video

EP. 8 Looking Into the Future and at Unmet Needs in EGFRm NSCLC

Video content above is prompted by the following:

How do you weigh different patient characteristics, such as molecular profile, disease burden, or CNS involvement, when deciding between monotherapy and combination approaches?

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