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Opinion|Videos|December 12, 2025

Ongoing Research to Watch at ASH 2025 and Beyond

Author(s)Jonathan Webster, MD, Nikesh Shah, MD

Jonathan Webster, MD, and Nikesh Shah, MD, discuss ALL data and research to look out for at ASH 2025.

Episodes in this series

EP. 1 How Blinatumomab Is Utilized in ALL Management

EP. 1 How Blinatumomab Is Utilized in ALL Management

EP. 2 Current Frontline Treatment Considerations in Acute Lymphoblastic Leukemia

EP. 2 Current Frontline Treatment Considerations in Acute Lymphoblastic Leukemia

EP. 3 Role of Age and Ph Status in Blinatumomab Selection in ALL

EP. 3 Role of Age and Ph Status in Blinatumomab Selection in ALL

EP. 4 Outcomes With Blinatumomab in Younger Adults With BCR:ABL1–negative B-ALL

EP. 4 Outcomes With Blinatumomab in Younger Adults With BCR:ABL1–negative B-ALL

EP. 5 Other Possible Research Avenues for Blinatumomab in ALL

EP. 5 Other Possible Research Avenues for Blinatumomab in ALL

EP. 6 Ongoing Research to Watch at ASH 2025 and Beyond

EP. 6 Ongoing Research to Watch at ASH 2025 and Beyond

Jonathan Webster, MD, and Nikesh Shah, MD, highlight key ALL data anticipated at the 2025 ASH Annual Meeting, including updates from pivotal immunotherapy studies and trials exploring targeted agents. They discuss how these findings may refine treatment selection, deepen understanding of MRD-guided care, and influence long-term management strategies. They also identify emerging areas of scientific interest that may define the next wave of innovation in ALL research.

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