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Opinion|Videos|December 12, 2025

Other Possible Research Avenues for Blinatumomab in ALL

Author(s)Jonathan Webster, MD, Nikesh Shah, MD

Ongoing research explores the logistics and efficacy of blinatumomab, aiming to enhance patient access and treatment outcomes in leukemia therapy.

Episodes in this series

EP. 1 How Blinatumomab Is Utilized in ALL Management

EP. 1 How Blinatumomab Is Utilized in ALL Management

EP. 2 Current Frontline Treatment Considerations in Acute Lymphoblastic Leukemia

EP. 2 Current Frontline Treatment Considerations in Acute Lymphoblastic Leukemia

EP. 3 Role of Age and Ph Status in Blinatumomab Selection in ALL

EP. 3 Role of Age and Ph Status in Blinatumomab Selection in ALL

EP. 4 Outcomes With Blinatumomab in Younger Adults With BCR:ABL1–negative B-ALL

EP. 4 Outcomes With Blinatumomab in Younger Adults With BCR:ABL1–negative B-ALL

EP. 5 Other Possible Research Avenues for Blinatumomab in ALL

EP. 5 Other Possible Research Avenues for Blinatumomab in ALL

EP. 6 Ongoing Research to Watch at ASH 2025 and Beyond

EP. 6 Ongoing Research to Watch at ASH 2025 and Beyond

Jonathan Webster, MD, and Nikesh Shah, MD, explore future research directions for blinatumomab in ALL, including combination strategies, sequencing questions, and potential synergy with next-generation targeted agents. They also consider how novel immunotherapies and evolving MRD-driven treatment paradigms may shape upcoming clinical investigations.

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