
Opinion|Videos|October 14, 2024
Optimizing Ovarian Cancer Care: PARP Resistance, Management of Oligoprogression, and Adverse Event Mitigation
Panelists discuss strategies to address PARP inhibitor (PARPi) resistance in ovarian cancer, including emerging combinations like gotistobart + pembrolizumab from the PRESERVE-004 trial, insights from the SOPRANO trial on managing oligometastases or oligoprogression, and approaches to mitigate or manage common adverse events associated with PARPi maintenance therapy.
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Video content above is prompted by the following:
- Please comment on PARP inhibitor (PARPi) resistance. Are there promising strategies to overcome this challenge?
- PRESERVE-004 gotistobart + pembrolizumab
- Others?
- What insights can be drawn from the SOPRANO trial findings regarding the management of oligometastases or oligoprogression in ovarian cancer?
- What adverse events are most commonly seen with PARPi maintenance therapy and how do you mitigate or manage these?
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