
Opinion|Videos|October 21, 2024
Navigating Treatment Strategies for Advanced Cervical Cancer: Localized Therapy, KEYNOTE-A18 Trial Data, and Frontline Approaches
Panelists discuss key findings from the KEYNOTE-A18 trial, which evaluated pembrolizumab in combination with chemoradiotherapy for high-risk locally advanced cervical cancer, highlighting the implications for treatment approaches in this patient population.
Advertisement
Episodes in this series

Video content above is prompted by the following:
- Briefly review the available treatment options for advanced cervical cancer.
- In which patients may you opt for localized therapy? What is your preferred treatment strategy, and what factors influence your treatment decision?
- Briefly comment on key findings, including overall survival data from the KEYNOTE-A18 trial, evaluating pembrolizumab + chemoradiotherapy in high-risk locally advanced cervical cancer.
- What implications do these findings have, and what impact may they have on your treatment approach for high-risk cervical cancer?
- In which patients may you forgo localized therapy? What is your preferred frontline treatment approach, and why?
- What is your next-line treatment strategy for patients who experience disease relapse on frontline therapy?
Advertisement
Related to this article

Did you catch all of this week's top oncology news? Test your knowledge with OncLive's Weekly News Quiz.

Durvalumab plus BCG is now an approved first-line option for high-risk NMIBC, but better BCG delivery and biomarker-guided selection should shape its use.

The FDA has approved amivantamab and hyaluronidase-lpuj for metastatic head and neck squamous cell carcinoma.

A UCLA-led study suggests routine mammograms or other breast imaging may not benefit women after double mastectomy for DCIS.
Advertisement
Advertisement
Trending on OncLive
1
FDA Approves Amivantamab and Hyaluronidase for Metastatic HNSCC
2
BCG Optimization Becomes a Priority as Durvalumab Gains a Role in High-Risk NMIBC
3
Dr Cai on the Rationale for Evaluating Rocbrutinib Plus R-CHOP in Non-GCB DLBCL and MCL
4
Dr Skoulidis on Divarasib vs Sotorasib or Adagrasib in KRAS G12C–Mutated NSCLC
5




