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Role of Allogeneic Transplants in Hematologic Malignancies

Experts discuss what role allogeneic transplants play in hematologic malignancies, specifically in AML and ALL.

This is a video synopsis/summary of a Peer Exchange featuring Miguel-Angel Perales, MD; Nelli Bejanyan, MD; Amandeep Salhotra, MD; and Arpita Gandhi, MD, MS.

The discussion focuses on the role of allogeneic hematopoietic stem cell transplantation in hematologic malignancies, particularly acute myeloid leukemia and acute lymphoblastic leukemia (ALL). Despite the advent of novel therapies, allogeneic transplantation remains the only curative option for many patients with high-risk features. Data from the Center for International Blood and Marrow Transplant Research shows improved outcomes for ALL patients undergoing allogeneic transplantation over time. The increasing use of alternative donors has made it possible for most patients in need of transplantation to find a suitable donor.

Video synopsis is AI-generated and reviewed by OncLive® editorial staff.

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