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Opinion|Videos|December 15, 2023

Role of Allogeneic Transplants in Hematologic Malignancies

Author(s)Miguel-Angel Perales, MD, Nelli Bejanyan, MD, Amandeep Salhotra, MD

Experts discuss what role allogeneic transplants play in hematologic malignancies, specifically in AML and ALL.

Episodes in this series

A panel of 4 experts on allogeneic transplant

EP. 1 Role of Allogeneic Transplants in Hematologic Malignancies

A panel of 4 experts on hematologic malignancies

EP. 2 Hematologic Malignancies and Transplant Options and Conditioning Regimens Used in Allo-HSCT

A panel of 4 experts on hematologic malignancies

EP. 3 Supportive Care Measures for Patients Planning to Receive an Allogenic Transplant

A panel of 4 experts on hematologic malignancies

EP. 4 Transplant Complications and Survival Outcomes

A panel of 4 experts on hematologic malignancies

EP. 5 Clinical Trial Update: CTN Trial

A panel of 4 experts on hematologic malignancies

EP. 6 Graft-versus-Host Disease Prophylaxis and Management

A panel of 4 experts on hematologic malignancies

EP. 7 Patient Case Studies of GvHD

A panel of 4 experts on hematologic malignancies

EP. 8 Emerging Cellular Therapies in Hematologic Malignancies

A panel of 4 experts on hematologic malignancies

EP. 9 Transplant in the Elderly Population

A panel of 4 experts on hematologic malignancies

EP. 10 Toxicity Assessment of Precision-Engineered Allo-HSCT

A panel of 4 experts on hematologic malignancies

EP. 11 The Role of Allo-HSCT in Higher-Risk MDS

A panel of 4 experts on hematologic malignancies

EP. 12 Investigational Allo-HSCT for Advanced Hematologic Malignancies

A panel of 4 experts on hematologic malignancies

EP. 13 The Future of Allo-HSCT and Cellular Therapies

A panel of 4 experts on hematologic malignancies

EP. 14 OncLive Peer Exchange on Allo-HSCT: Conclusion of Discussion

This is a video synopsis/summary of a Peer Exchange featuring Miguel-Angel Perales, MD; Nelli Bejanyan, MD; Amandeep Salhotra, MD; and Arpita Gandhi, MD, MS.

The discussion focuses on the role of allogeneic hematopoietic stem cell transplantation in hematologic malignancies, particularly acute myeloid leukemia and acute lymphoblastic leukemia (ALL). Despite the advent of novel therapies, allogeneic transplantation remains the only curative option for many patients with high-risk features. Data from the Center for International Blood and Marrow Transplant Research shows improved outcomes for ALL patients undergoing allogeneic transplantation over time. The increasing use of alternative donors has made it possible for most patients in need of transplantation to find a suitable donor.

Video synopsis is AI-generated and reviewed by OncLive® editorial staff.

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