Opinion|Videos|April 10, 2026

Treatment Adhereance and AE Management With Sevabertinib in HER2-Mutant NSCLC

Martin F. Dietrich, MD, PhD, and Ticiana Leal, MD, discuss toxicity management with TKIs in HER2-mutant non–small cell lung cancer.

Martin F. Dietrich, MD, PhD, and Ticiana Leal, MD, discuss strategies to optimize adherence and manage adverse effects associated with HER2-targeted TKIs. Dietrich outlines common toxicities and the need for proactive monitoring and early intervention. Leal highlights the role of dose modifications and patient education in maintaining treatment continuity and maximizing therapeutic benefit.


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