Hematologic Oncology | Specialty

The OncLive Hematology Oncology condition center page is a comprehensive resource for clinical news and expert insights on various hematologic malignancies, including leukemias, lymphomas, myeloproliferative neoplasms, multiple myeloma, and much more. This section features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in hematologic cancers.

FDA Grants Priority Review to Abatacept for Prevention of Acute GVHD

August 23rd 2021

The FDA has granted a priority review designation to a supplemental biologics license application seeking the approval of abatacept for the prevention of moderate to severe acute graft-versus-host disease in patients aged 6 years and older who are receiving unrelated donor hematopoietic stem cell transplantation.

Exploring Emerging Data in DLBCL 

August 23rd 2021

A panel of experts in lymphoma reflect on major data that came out of the ASCO 2021 Virtual Meeting.

Looking at the Big Picture in DLBCL 

August 23rd 2021

Key opinion leaders in lymphoma take a look at challenges in treating B-cell lymphoma and where they see the things moving in the future.

Treating Patients Post CAR T Therapy

August 23rd 2021

David Rizzieri, MD, discusses treatment approaches for after relapse on CAR T cell therapy or for patients who are ineligible for CAR T therapy.

Success Beyond Science: Becoming a Hematologist/Oncologist

August 22nd 2021

The ability to reflect and boldly choose a professional identity should be discussed, encouraged, and nurtured in every individual.

Clonal Hematopoiesis Confers Substantial Risks in Healthy Individuals and Patients with Cancer

August 20th 2021

Peter G. Miller, MD, PhD, discusses the characteristics and risks associated with clonal hematopoiesis and risk-stratification efforts for patients with cancer who are at risk of developing therapy-related secondary malignancies from clonal hematopoiesis.

Mosunetuzumab Elicits Durable Response in Elderly Patients With DLBCL

August 20th 2021

Updated outcomes from the ongoing phase 1/2 GO40554 trial show that mosunetuzumab monotherapy demonstrated promising efficacy and a tolerable safety for elderly/unfit patients with previously untreated first-line diffuse large B-cell lymphoma.

Treatment in Older Patients with High-Risk MDS

August 20th 2021

Azra Raza, MD, discusses considerations for use of hypomethylating agents in older patients with high-risk myelodysplastic syndrome.

Role of Transplant in MDS

August 20th 2021

The panel of experts comment on the role of transplant in patients with myelodysplastic syndrome.

High-Risk MDS: Clinical Efficacy Data

August 19th 2021

Mikkael A. Sekeres, MD, discusses his approach to treatment in patients with high-risk MDS incorporating efficacious clinical trial data.

Clinical Implications of High-Risk MDS

August 19th 2021

Experts in the treatment of MDS discuss the clinical implications and treatment selection for patients with high-risk MDS.

The Role of Venetoclax for Treatment of AML

August 19th 2021

Renowned experts in hematology-oncology provide insight into the practical implications of treating acute myeloid leukemia with the current standard-of-care regimen using venetoclax.

Venetoclax Combination Therapy for IDH-mutated AML

August 19th 2021

Key opinion leader in the management of acute myeloid leukemia, Harry Erba, MD PhD, builds a conversation on the use of venetoclax as a part of combination therapy in patients with IDH mutations.

Zandelisib/Zanubrutinib Produces Promising Safety, Efficacy in Relapsed/Refractory B-Cell Malignancies

August 18th 2021

Alexey V. Danilov, MD, discusses the safety and efficacy achieved with the novel combination comprised of zandelisib and zanubrutinib in patients with relapsed/refractory B-cell malignancies.

Approaches to Treatment for Relapsed/Refractory ALL

August 17th 2021

Ibrahim Aldoss, MD and James K. McCloskey, MD describe treatment modalities that can be utilized in treating a pediatric or AYA patient with relapsed / refractory ALL.

Approaches to Treatment After Failure to Achieve MRD Negativity

August 17th 2021

Insights on how to approach an acute lymphocytic leukemia patient who is MRD positive after induction therapy.

Case 1: Treatment Algorithm and Supportive Care Recommendations

August 16th 2021

Patricia Lugar, MD, MS, shares treatment algorithm and supportive care recommendations for a 75-year-old man with systemic mastocytosis.

Dr. Miller on the Characteristics of Clonal Hematopoiesis

August 16th 2021

Peter G. Miller, MD, PhD, discusses the characteristics of clonal hematopoiesis.

Case 1: Treatment and Management Considerations

August 16th 2021

The panel of experts in SM discuss the diagnosis and management of a 75-year-old man with systemic mastocytosis.

Frontline Targeted Therapy in CLL: Tolerability and Toxicity Management

August 16th 2021

A comprehensive breakdown of the tolerability of frontline targeted therapies used to manage chronic lymphocytic leukemia and toxicity management.