Navigating the Future of Cutaneous Squamous Cell Carcinoma (cSCC): An Expert Discussion on Modern Immunotherapy

Panelists discuss best practices for evaluating suspected cSCC, including lesion assessment, biopsy strategies, and initial patient workup.

Panelists discuss clinical and pathological factors used to stratify cSCC into low-, high-, and very high-risk categories.

Panelists discuss how dermatologists serve as the first line of detection and play an essential role in early management and triage of cSCC.

Panelists discuss when cSCC can be managed within dermatology and when multidisciplinary referral is warranted.

Panelists discuss the importance of following evidence-based clinical pathways and national guidelines to streamline cSCC care.

Panelists discuss patient populations requiring earlier biopsy and aggressive workup to detect high-risk cSCC.

Panelists discuss standard primary treatment modalities for cSCC, emphasizing surgical control and selective use of adjunctive therapy.

Panelists discuss how to identify appropriate surgical candidates and coordinate timely referral to specialized surgical teams.

Panelists discuss when radiation therapy is appropriate for treating cSCC, and how it complements surgical management.

Panelists discuss the growing use of systemic immunotherapy for advanced or unresectable cSCC and how it integrates with other modalities.

Panelists discuss ongoing clinical trials, including adjuvant immunotherapy studies, and identify which patients are most likely to benefit from these strategies.

Panelists discuss how clinicians identify which patients are most likely to benefit from adjuvant immunotherapy based on clinical and pathologic risk factors.

Panelists discuss ongoing clinical trials evaluating adjuvant immunotherapy for cSCC and the implications of early outcomes for clinical practice.

Panelists discuss strategies for long-term surveillance and management of patients with cSCC who have received adjuvant immunotherapy.

Panelists discuss strategies for integrating dermatology, surgery, radiation, and oncology to deliver cohesive, patient-centered cSCC care.