May 2014 | OncologyLive

Targeted Therapy Challenges:More Cancer Genes Discovered, Mutational Burdens Defined

June 13, 2014

Even as technological advances make it possible to sequence DNA on a large scale at relatively lower costs and in shorter time-frames, emerging evidence from the world's top research laboratories suggests that scientists are still a long way from having a complete catalog of cancer genes.

RAS Mutations Ready for Prime Time in mCRC

June 12, 2014

A multitude of studies presented over the course of the past year have emphasized the importance of broader RAS mutational analyses outside of traditional KRAS testing for patients with metastatic colorectal cancer.

USPSTF, ASCO Issue More Guidance on Genetic Testing Based on Family History

June 11, 2014

Oncology practitioners now have several resources to consult for advice on genetic testing for their patients following the US Preventive Services Task Force (USPSTF) December 2013 update of its 2005 BRCA recommendations.

Radium 223 Option Hinges on Bony Disease Burden in mCRPC

June 05, 2014

As with other new therapies that have been approved in recent years for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC), researchers are not entirely certain about how best to fit radium Ra 223 dichloride (Xofigo) into the emerging paradigm

Nab-Paclitaxel Explored as Adjuvant Therapy in Pancreatic Cancer

June 04, 2014

While the combination of gemcitabine and nab-paclitaxel (Abraxane) has demonstrated survival benefits for patients with metastatic pancreatic cancer, oncologists are interested in knowing whether the regimen will transfer well into the adjuvant setting

How Einhorn Helped Turn a Deadly Cancer Into a Curable Disease

May 28, 2014

Einhorn, now a distinguished professor and Livestrong Foundation Professor of Oncology at the IU School of Medicine, has driven other major advances in the treatment of testicular cancer, coming up with a more effective and less toxic standard regimen and revealing important principles that are being applied to the treatment of other cancer types.

New Model for Outpatient Induction Chemotherapy for AML and MDS Explored

May 28, 2014

Although many patients with cancer now receive chemotherapy as outpatients, most cancer treatment centers do not extend this practice to patients with acute myeloid leukemia (AML) or advanced myelodysplastic syndromes (MDS) who are receiving initial intensive induction therapy.

HPV Test With Genotyping Tops Cervical Cancer Screening Strategies

May 27, 2014

Cervical cancer screening based on identification of human papillomavirus (HPV) strains outperformed primary liquid cytology for detection of high-grade cervical intraepithelial neoplasia (CIN), data from a large cohort study showed.

On the Genome Journey

May 07, 2014

When the mapping of the human genome was completed more than a decade ago, there was unbridled excitement about the impact that the wealth of new knowledge would have on medicine, particularly on cancer treatment.