Vol. 19/No. 21 | OncologyLive

Hispanics Are at Highest Risk of Neurotoxicity From Chemotherapy for ALL

November 12, 2018

Ethnic differences in the prevalence of neurotoxicity from methotrexate therapy may help explain why minority patients, specifically Hispanics, experience disparities in treatment outcomes for pediatric acute lymphoblastic leukemia.

Modern Therapies Expand Options for Soft-Tissue Sarcomas

November 08, 2018

Although soft-tissue sarcoma is seldom diagnosed in adults, the development of several new therapies in recent years for patients with rare subtypes is energizing leaders in the field and underscoring the need for a multidisciplinary approach to care.

Hospital Lauded for Innovative Solution to Drug Waste Problem

November 07, 2018

Within a year of starting its drug-waste reduction study in 2010, NCCH became the first hospital in the country to implement a program systematically extending medications’ beyond use dates from several hours to upward of 7 days.

Prodrugs in Oncology: Teaching Old and New Drugs More Tricks

November 07, 2018

As researchers gain a better understanding of the unique aspects of individual tumor types and their surrounding microenvironment, the design of novel therapies categorized as prodrugs is become increasingly sophisticated, and several novel constructs show particular promise.

ASCO Urges Routine dMMR Testing for Second-Line Metastatic Pancreatic Cancer

November 05, 2018

Based on fresh studies in the setting of metastatic pancreatic cancer, the American Society of Clinical Oncology now recommends routine testing for mismatch repair deficiency or high microsatellite instability for candidates for checkpoint inhibitor therapy.