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Opinion|Videos|January 9, 2026

CAR T-Cell Therapy Targets Beyond BCMA in Multiple Myeloma

Author(s)Krina K. Patel, MD, MSc, Matthew J. Frigault, MD

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, discuss potential targets for novel CAR T-cell therapies in multiple myeloma.

Episodes in this series

2 experts are featured in this series

EP. 1 Treatment Approaches for Multiple Myeloma in the Fourth Line and Beyond

2 experts are featured in this series

EP. 2 Rationale Driving Additional CAR T-Cell Therapy Research in Myeloma

2 experts are featured in this series

EP. 3 Role of Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

2 experts are featured in this series

EP. 4 Exploring the Novel CAR T-Cell Therapy Anito-Cel in Multiple Myeloma

2 experts are featured in this series

EP. 5 iMMagine-1 Trial: Data for Anito-Cel in R/R Myeloma After 3 Prior Lines of Therapy

2 experts are featured in this series

EP. 6 CAR T-Cell Therapy Targets Beyond BCMA in Multiple Myeloma

2 experts are featured in this series

EP. 7 Other Key Myeloma CAR T-Cell Therapy Data From ASH 2025

2 experts are featured in this series

EP. 8 Persisting Questions With CAR T-Cell Therapy in Multiple Myeloma

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, discuss emerging CAR T-cell targets beyond BCMA in multiple myeloma. They highlight alternative antigens under investigation and the rationale for diversifying therapeutic targets. Patel and Frigault explain how these strategies may help overcome resistance and improve long-term disease control.

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