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Opinion|Videos|December 23, 2025

Rationale Driving Additional CAR T-Cell Therapy Research in Myeloma

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, detail the drive beyond additional CAR T-cell therapy research in multiple myeloma.

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, explore the scientific and clinical rationale supporting continued CAR T-cell therapy research in multiple myeloma. They discuss limitations of existing products, including durability of response and access challenges. Patel and Frigault explain how next-generation constructs aim to address these unmet needs.

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