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Opinion|Videos|January 2, 2026

Role of Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, explain the role of bridging therapy alongside CAR T-cell therapy in multiple myeloma.

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, examine the role of bridging therapy during CAR T-cell manufacturing for patients with multiple myeloma. They discuss factors that influence bridging strategy selection, including disease burden and timing considerations. Patel and Frigault emphasize balancing disease control with preservation of T-cell fitness.

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