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Opinion|Videos|January 16, 2026

Persisting Questions With CAR T-Cell Therapy in Multiple Myeloma

Author(s)Krina K. Patel, MD, MSc, Matthew J. Frigault, MD

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, discuss questions ongoing research with CAR T-cell therapy in multiple myeloma aims to address.

Episodes in this series

2 experts are featured in this series

EP. 1 Treatment Approaches for Multiple Myeloma in the Fourth Line and Beyond

2 experts are featured in this series

EP. 2 Rationale Driving Additional CAR T-Cell Therapy Research in Myeloma

2 experts are featured in this series

EP. 3 Role of Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

2 experts are featured in this series

EP. 4 Exploring the Novel CAR T-Cell Therapy Anito-Cel in Multiple Myeloma

2 experts are featured in this series

EP. 5 iMMagine-1 Trial: Data for Anito-Cel in R/R Myeloma After 3 Prior Lines of Therapy

2 experts are featured in this series

EP. 6 CAR T-Cell Therapy Targets Beyond BCMA in Multiple Myeloma

2 experts are featured in this series

EP. 7 Other Key Myeloma CAR T-Cell Therapy Data From ASH 2025

2 experts are featured in this series

EP. 8 Persisting Questions With CAR T-Cell Therapy in Multiple Myeloma

Krina K. Patel, MD, MSc, and Matthew J. Frigault, MD, address key unanswered questions surrounding the use of CAR T-cell therapy in multiple myeloma. They discuss issues such as optimal timing, durability of benefit, retreatment strategies, and combination approaches. Patel and Frigault conclude the program with an outro reflecting on how ongoing research may shape the future of CAR T-cell therapy in myeloma care.

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