Opinion|Videos|February 4, 2025
Cilta-Cel in Early R/R MM: Evolving CAR T Data from CARTITUDE-4
Panelists discuss the latest efficacy data from the CARTITUDE-4 study evaluating ciltacabtagene autoleucel (cilta-cel) in relapsed/refractory multiple myeloma (R/R MM), the significance of minimal residual disease (MRD) negativity, and how real-world and patient-reported outcomes influence the decision to use chimeric antigen receptor (CAR) T-cell therapy for early-stage R/R MM. They also compare standard-of-care idecabtagene vicleucel (ide-cel) and cilta-cel in this patient population.
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Episodes in this series
Video content above is prompted by the following:
- Please comment on the latest efficacy data from CARTITUDE-4, evaluating cilta-cel in patients with R/R MM.
- CARTITUDE-4, MRD negativity
- How do real-world and/or patient-reported outcomes inform your decision of CAR T for early-stage R/R MM?
- CARTITUDE-4, patient-reported outcomes
- Comparison, standard-of-care ide-cel and cilta-cel in R/R MM:
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Did you catch all of this week's top oncology news? Test your knowledge with OncLive's Weekly News Quiz.
The FDA received a BLA for etentamig in relapsed/refractory multiple myeloma, based on response and PFS gains in the phase 3 CERVINO trial.
Elranatamab improved PFS vs 3 standard regimens in relapsed/refractory multiple myeloma in the phase 3 MagnetisMM-32 trial.
The FDA approved dostarlimab in rectal cancer and pembrolizumab in tumors with high mutational burden, Europe cleared teclistamab in myeloma, and more.
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