
Opinion|Videos|February 11, 2025
Weighing CAR T Toxicity Profiles in Early R/R MM
Panelists discuss how recent data from the KarMMa-3 study influence the decision to treat early-stage relapsed/refractory multiple myeloma (R/R MM) with idecabtagene vicleucel (ide-cel), as well as the key toxicities considered when selecting chimeric antigen receptor (CAR) T-cell therapy. They also explore how these toxicities impact the transition of patients back to the community setting post CAR T and share strategies for managing early- and late-stage toxicities.
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Video content above is prompted by the following:
- Dr Rodriguez to Dr Neparidze: What toxicities do you weigh most when deciding which CAR T to use for early R/R MM?
- Dr Rodriguez to faculty: Post CAR T, how do those toxicities impact when you transition your patients back to the community setting?
- Dr Rodriguez to faculty: What strategies would you advise for managing and mitigating early- vs late-stage toxicities?
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Related to this article

Did you catch all of this week's top oncology news? Test your knowledge with OncLive's Weekly News Quiz.

An OncLive Scientific Interchange and Workshop covered sequencing, toxicity management, and access barriers for CAR T-cell therapy in multiple myeloma.

Readouts across LBCL, relapsed/refractory myeloma, and CALR-mutated myelofibrosis anchored the hematology data presented at EHA 2026.

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In case you missed any, check out our recap of the episodes of OncLive On Air that aired in June 2026.

Did you catch all of this week's top oncology news? Test your knowledge with OncLive's Weekly News Quiz.
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