
Opinion|Videos|March 26, 2025
Clinical Insights: Incorporating Zanidatamab and Other HER2-Targeted Agents Into the Real-World Practice in Advanced BTC
Panelists discuss how treatment selection among HER2-targeted agents for biliary tract cancer (BTC) depends on multiple factors including patient characteristics and prior therapies, while also considering the role of traditional chemotherapy regimens such as FOLFOX in specific clinical scenarios.
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Video content above is prompted by the following:
- What is your general treatment approach when deciding among the available HER2-targeted agents? For those with HER2-positive tumors, are there situations in which you may still proceed with a 5-FU–containing regimen such as FOLFOX?
- Please comment on any differences and/or similarities in practice regarding HER2-directed therapy selection. Please describe any specific patient and/or disease factors considerations in your treatment approach.
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