Opinion|Videos|March 19, 2025

New Approvals in HER2-Positive BTC: Zanidatamab - Key Findings from HERIZON-BTC-01 Study

Panelists discuss how the HERIZON-BTC-302 study demonstrated zanidatamab's efficacy in HER2-positive biliary tract cancer (BTC) with key end points presented at ASCO GI, while sharing insights on optimal dosing strategies and early real-world experience with this newly approved agent in the second-line setting.

Video content above is prompted by the following:

  • Zanidatamab was recently approved. What were some key end points from the HERIZON-BTC-302 study at ASCO GI and what are your impressions?
  • What is your dosing strategy with zanidatamab? Dr Ellis, can you share some highlights from a poster looking at optimizing zanidatamab’s dosing?
  • For those with experience using zanidatamab in the 2L, what has your experience been? What outcomes have you seen in patients so far?

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