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Opinion|Videos|January 6, 2026

Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

Author(s)Maximilian Merz, MD, Carrie Bellerive, BS, RN, BMTCN

Maximilian Merz, MD, and Carrie Bellerive, BS, RN, BMTCN, detail current expectations with manufacturing processes for CAR T-cell therapy.

Episodes in this series

EP. 1 How CAR T-Cell Therapy Has Affected Clinical Management of Multiple Myeloma

EP. 1 How CAR T-Cell Therapy Has Affected Clinical Management of Multiple Myeloma

EP. 2 The Role of Treatment Center Coordinators for CAR T-Cell Therapy Administration in Myeloma

EP. 2 The Role of Treatment Center Coordinators for CAR T-Cell Therapy Administration in Myeloma

EP. 3 Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

EP. 3 Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

EP. 4 Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

EP. 4 Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

EP. 5 Data for Out-of-Specification Cilta-Cel in R/R Multiple Myeloma

EP. 5 Data for Out-of-Specification Cilta-Cel in R/R Multiple Myeloma

EP. 6 Key Updates With CAR T-Cell Therapy in Myeloma From ASH 2025

EP. 6 Key Updates With CAR T-Cell Therapy in Myeloma From ASH 2025

EP. 7 Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

EP. 7 Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

Maximilian Merz, MD, and Carrie Bellerive, BS, RN, BMTCN, detail current expectations and realities surrounding commercial manufacturing of CAR T-cell therapies. They discuss timelines, quality control considerations, and logistical challenges that can affect treatment planning. Merz and Bellerive also address how evolving manufacturing processes may improve access and reliability over time.

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