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Opinion|Videos|January 6, 2026

Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

Author(s)Maximilian Merz, MD, Carrie Bellerive, BS, RN, BMTCN

Maximilian Merz, MD, and Carrie Bellerive, BS, RN, BMTCN, discuss considerations for bridging therapy ahead of CAR T-cell therapy in multiple myeloma.

Episodes in this series

EP. 1 How CAR T-Cell Therapy Has Affected Clinical Management of Multiple Myeloma

EP. 1 How CAR T-Cell Therapy Has Affected Clinical Management of Multiple Myeloma

EP. 2 The Role of Treatment Center Coordinators for CAR T-Cell Therapy Administration in Myeloma

EP. 2 The Role of Treatment Center Coordinators for CAR T-Cell Therapy Administration in Myeloma

EP. 3 Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

EP. 3 Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

EP. 4 Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

EP. 4 Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

EP. 5 Data for Out-of-Specification Cilta-Cel in R/R Multiple Myeloma

EP. 5 Data for Out-of-Specification Cilta-Cel in R/R Multiple Myeloma

EP. 6 Key Updates With CAR T-Cell Therapy in Myeloma From ASH 2025

EP. 6 Key Updates With CAR T-Cell Therapy in Myeloma From ASH 2025

EP. 7 Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

EP. 7 Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

Maximilian Merz, MD, and Carrie Bellerive, BS, RN, BMTCN, discuss key considerations when selecting and managing bridging therapy prior to CAR T-cell infusion in multiple myeloma. They examine how disease burden, prior treatments, and manufacturing timelines influence bridging strategy choices. Merz and Bellerive emphasize balancing disease control with preservation of T-cell fitness ahead of infusion.

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