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Opinion|Videos|January 20, 2026

Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

Author(s)Maximilian Merz, MD, Carrie Bellerive, BS, RN, BMTCN

Maximilian Merz, MD, and Carrie Bellerive, BS, RN, BMTCN, discuss future research directions for CAR T-cell therapy in multiple myeloma.

Episodes in this series

EP. 1 How CAR T-Cell Therapy Has Affected Clinical Management of Multiple Myeloma

EP. 1 How CAR T-Cell Therapy Has Affected Clinical Management of Multiple Myeloma

EP. 2 The Role of Treatment Center Coordinators for CAR T-Cell Therapy Administration in Myeloma

EP. 2 The Role of Treatment Center Coordinators for CAR T-Cell Therapy Administration in Myeloma

EP. 3 Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

EP. 3 Current Expectations With Commercial Manufacturing of CAR T-Cell Therapy

EP. 4 Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

EP. 4 Navigating Bridging Therapy With CAR T-Cell Therapy in Multiple Myeloma

EP. 5 Data for Out-of-Specification Cilta-Cel in R/R Multiple Myeloma

EP. 5 Data for Out-of-Specification Cilta-Cel in R/R Multiple Myeloma

EP. 6 Key Updates With CAR T-Cell Therapy in Myeloma From ASH 2025

EP. 6 Key Updates With CAR T-Cell Therapy in Myeloma From ASH 2025

EP. 7 Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

EP. 7 Pressing Questions to Address With Ongoing Research With CAR T-Cell Therapy in Myeloma

Maximilian Merz, MD, and Carrie Bellerive, BS, RN, BMTCN, explore key unanswered questions guiding ongoing CAR T-cell therapy research in multiple myeloma. They discuss areas such as earlier-line use, durability of response, retreatment strategies, and combination approaches. Merz and Bellerive conclude by emphasizing how continued research will shape the future integration of CAR T-cell therapy into myeloma care.

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Beth Faiman, PhD, MSN, APN-BC, BMTCN, AOCN, FAAN, FAPO; Beth Sandy, MSN, CRNP, FAPO; Lindsay Adkins, MSN, FNP-BC, BMTCN; Jeneth Aquino, DNP, FNP-BC; Casey Gormley, MSN, FNP-C, AOCNP; Heather J. Jackson, PhD, FNP-BC; Kelsey Martin, AG-ACNP-BC, AOCNP; Nerina T. McDonald, PA-C; Lauren Verity Moore, DNP, MSN, AGACNP-BC; Faith A. Mutale, DNP, CRNP; Tiffany Richards, PhD, ANP-BC, AOCNP; Emily Skotte, DNP, MSN, ACNP-BC; Leslie Smith, DNP, RN, APRN-CNS, AOCNS, BMTCN; Saneese Stephen, PA-C, MPAS; Sara M. Tinsley-Vance, PhD, APRN, AOCN

Community Practice Connections™: DLL3-Targeting Bispecific Antibodies for Small Cell Lung Cancer—From Innovation to Practice

Community Practice Connections™: DLL3-Targeting Bispecific Antibodies for Small Cell Lung Cancer—From Innovation to Practice

Jacob Sands, MD; Anne Chiang, MD, PhD

The Rise of Novel HER2-Targeting Therapies in GEA: Mechanisms and Clinical Data

The Rise of Novel HER2-Targeting Therapies in GEA: Mechanisms and Clinical Data

Rahul Gosain, MD, MBA; Rohit Gosain, MD

(Pharmacist Track) Tackling Oncologic Emergencies in Patients Treated With High-Dose Methotrexate

(Pharmacist Track) Tackling Oncologic Emergencies in Patients Treated With High-Dose Methotrexate

Shazia Nakhoda, MD; Shruti Gupta, MD, MPH; Anitha Varghese, MSN, APRN, AGPCNP-C

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