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Opinion|Videos|July 2, 2024

Dr Voss Shares Highlights from the COSMIC-313 and LITESPARK-024 Trials

Author(s)Pedro Barata, MD, MSc, Martin H. Voss, MD, Elizabeth Wulff-Burchfield, MD

Martin Voss, MD, discusses the subgroup analysis of the COSMIC-313 study, which investigated the combination of nivolumab, ipilimumab, with or without cabozantinib (nivo + ipi +/- cabo), focusing on the potential advantages this treatment approach may offer for patients with intermediate to high-risk renal cell carcinoma (RCC).

Episodes in this series

4 KOLs are featured in this series

EP. 1 Treatment Selection in the Frontline Setting of Advanced Clear Cell RCC

4 KOLs are featured in this series

EP. 2 Dr Wulff-Burchfield Reviews CheckMate 214 and CheckMate 9ER

4 KOLs are featured in this series

EP. 3 Dr Xu Reviews Data from the CLEAR Trial and Recent Analyses at ASCO 2024 - Lenvatinib + Pembrolizumab in Frontline Advanced RCC

4 KOLs are featured in this series

EP. 4 Dr Voss Shares Highlights from the COSMIC-313 and LITESPARK-024 Trials

4 KOLs are featured in this series

EP. 5 Exciting Data and Trials in Progress from ASCO 2024

4 KOLs are featured in this series

EP. 6 Ongoing RCC Clinical Trials that may Impact Practice

4 KOLs are featured in this series

EP. 7 Dr Xu Provides Clinical Perspective on the CONTACT-03 Trial Outcomes

4 KOLs are featured in this series

EP. 8 Dr Voss Application of Updated KEYNOTE-564 Data

4 KOLs are featured in this series

EP. 9 Guiding Sequencing & Finding a Contemporary Regimen/ Approach to Treatment Post-Checkpoint Inhibition

4 KOLs are featured in this series

EP. 10 World Health Organization (WHO) Classification Updates for Papillary RCC

4 KOLs are featured in this series

EP. 11 Additional Forward-Looking Data and Studies Beyond Frontline Therapy in RCC

4 KOLs are featured in this series

EP. 12 The Role of Chemotherapy in nccRCC Treatment

4 KOLs are featured in this series

EP. 13 Select Ongoing Trials for nccRCC and Impact on the Treatment Landscape

4 KOLs are featured in this series

EP. 14 Final Thoughts/Looking Forward

Briefly comment on the COSMIC-313 nivo + ipi +/- cabo study in intermediate/high-risk patients subgroup analysis (Powles, et al. ASCO GU 2023: Abstract 605)
Dr Voss takes time to highlight the LITESPARK-024 trial = belzutifan + palbo > – (McDermott D, et al. ASCO 2023. Abstract TPS4603)

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