
Opinion|Videos|June 24, 2024
Dr Wulff-Burchfield Reviews CheckMate 214 and CheckMate 9ER
The panelists examine the latest findings from the CheckMate 214 trial, which assessed the combination of nivolumab and ipilimumab (nivo + ipi) as a first-line treatment for advanced renal cell carcinoma, focusing on efficacy, safety, and quality of life outcomes.
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Episodes in this series

- Please briefly discuss the recent data from the CheckMate 214 trial evaluating nivo + ipi for 1L treatment of advanced RCC.
- 8-year follow-up and subgroup analyses – please comment on OS, DOR, PFS, TFS, and safety (
Tannir et al., ASCO GU 2024 Abstract 363 ) - What insights do the recent HRQoL data provide? (
Cella et al., Oncologist Jan 2024 )
- 8-year follow-up and subgroup analyses – please comment on OS, DOR, PFS, TFS, and safety (
- Please comment on the role of doublet regimens in the 1L setting for advanced RCC and their recent data updates.
- CheckMate 9ER nivo + cabo
- 55-month follow up (
Bourlon et al., ASCO GU 2024 Abstract 362) - HRQoL (
Bedke et al., ASCO GU 2024 Abstract 384 ) - Partitioned 4-year OS (
Mantia et al., ASCO 2024 Abstract 4507 )
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