Opinion
Video
Frontline Treatment Options in Metastatic EGFR-Mutated NSCLC
Panelists discuss how, when discussing frontline regimens for EGFR-mutated non–small cell lung cancer (NSCLC), the NCCN-recommended options include osimertinib monotherapy for its targeted approach with lower toxicity; amivantamab/lazertinib combination for potentially deeper responses in specific mutations; and osimertinib with platinum-doublet chemotherapy for more aggressive disease requiring enhanced tumor control.
Video content above is prompted by the following:
- When discussing initial treatment options, how do you present the 3 recommended NCCN frontline regimens to patients: osimertinib monotherapy, amivantamab with lazertinib, and osimertinib combined with a platinum-containing doublet?
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