Opinion|Videos|March 31, 2025
Treatment Sequencing in the Second Line and Beyond in EGFR-Mutant NSCLC
Panelists discuss how, if the MARIPOSA trial shows an overall survival advantage exceeding 1 year, the amivantamab-lazertinib combination may see increased frontline use. Subsequent therapy options could include chemotherapy, targeted therapies based on resistance mechanisms, or clinical trials for emerging treatments.
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Video content above is prompted by the following:
If the MARIPOSA overall survival data exceeds a 1-year advantage as is projected, do you anticipate seeing the amivantamab with lazertinib combination used more frequently in the frontline setting? If so, what treatment options are available for subsequent therapy?
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