Opinion|Videos|March 7, 2025
Long-Term Data From CheckMate 9ER Investigating Nivolumab Plus Cabozantinib in Untreated Advanced RCC
Experts discuss the key findings from the final follow-up results of the CheckMate 9ER trial, evaluating nivolumab plus cabozantinib in advanced renal cell carcinoma (RCC) and share perspectives on the clinical implications of these updated data, along with insights from other studies of note, including LITESPARK-003 (belzutifan plus cabozantinib) and LITESPARK-024 (belzutifan plus palbociclib).
Advertisement
Episodes in this series
Video content above is prompted by the following:
- The CheckMate 9ER trial established the efficacy of nivolumab plus cabozantinib in advanced RCC. Could you review the key findings from the final follow-up results and share your perspectives on the clinical implications of these updated data?
- Please feel free to highlight other studies of note:
- LITESPARK-003 (belzutifan plus cabozantinib)
- LITESPARK-024 (belzutifan plus palbociclib)
- Please feel free to highlight other studies of note:
Advertisement
Related to this article
The top 5 OncLive TV videos of the week cover insights in ovarian cancer, breast cancer, head and neck cancer, pancreatic cancer, and follicular lymphoma.
Adanma Ayanambakkam, MD, MS, discusses findings from the FIT-001 trial of darlifarnib plus cabozantinib in RCC.
UroGen submitted an NDA for UGN-103 in recurrent NMIBC, T-DXd improved PFS in first-line HER2-mutant lung cancer, and more.
In a phase 1/2 study, the LSD1 inhibitor bomedemstat reduced spleen volume, improved symptoms, and lowered driver mutation burden in patients with advanced myelofibrosis.
Neeta Somaiah, MD, discusses the significance of the Peak study and what an approval of bezuclastinib plus sunitinib would mean for GIST.
Sara Nunnery, MD, MSCI, and Irene M. Kang, MD, discuss toxicity and monitoring considerations for the use of ADCs in metastatic TNBC.
The NMPA accepted the NDA for the PD-L1/4-1BB–directed bispecific antibody opamtistomig in previously treated advanced extrapulmonary NEC.
Obesity can weaken the immune system and lead to disease progression, but Roswell Park experts revealed that exercise may reverse that effect.
Advertisement
Advertisement
Trending on OncLive
1
ASCO Issues First Guideline on ctDNA Testing in Solid Tumors and Lymphoma
2
Intismeran Autogene Plus Pembrolizumab Meets RFS and DMFS End Points in Resected Stage IIB-IV Melanoma
3
Darlifarnib Plus Cabozantinib Displays Early Signals of Safety and Efficacy in RCC
4
The OncFive: Top Oncology Articles for the Week of 8/16
5