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Opinion|Videos|March 31, 2025

Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

Author(s)Surbhi Sidana, MD, Peter Voorhees, MD

Experts discuss where chimeric antigen receptor (CAR) T-cell therapy currently fits in the treatment paradigm, highlighting the patient factors and disease characteristics that influence its use in clinical decision-making.

Episodes in this series

EP. 1 Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

EP. 1 Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

EP. 2 Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

EP. 2 Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

EP. 3 Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM

EP. 3 Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM

EP. 4 Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

EP. 4 Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

EP. 5 Bridging to CAR T in R/R MM: Best Practices

EP. 5 Bridging to CAR T in R/R MM: Best Practices

EP. 6 Explaining CAR T: Key Points for Patient Counseling

EP. 6 Explaining CAR T: Key Points for Patient Counseling

EP. 7 Overcoming Barriers to CAR T Referral in R/R MM

EP. 7 Overcoming Barriers to CAR T Referral in R/R MM

EP. 8 Collaborative Approach in Managing Post CAR T Care Between Academic and Community Physicians in R/R MM

EP. 8 Collaborative Approach in Managing Post CAR T Care Between Academic and Community Physicians in R/R MM

EP. 9 Clinical Perspectives: Importance of Vaccinations and Infection Prevention Post CAR T, and Monitoring Strategies for Other Potential Late CAR T–Related Toxicities in R/R MM

EP. 9 Clinical Perspectives: Importance of Vaccinations and Infection Prevention Post CAR T, and Monitoring Strategies for Other Potential Late CAR T–Related Toxicities in R/R MM

EP. 10 Exciting Future Horizons for CAR T in MM and Take-Home Messages

EP. 10 Exciting Future Horizons for CAR T in MM and Take-Home Messages

Video content above is prompted by the following:

Where does CAR T-cell therapy currently fall in your treatment paradigm? What type of patient factors and/or disease characteristics influence your approach?

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