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Opinion|Videos|March 31, 2025

Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

Author(s)Surbhi Sidana, MD, Peter Voorhees, MD

Experts discuss their clinical approach to using chimeric antigen receptor (CAR) T-cell therapy in relapsed/refractory multiple myeloma (R/R MM), focusing on how they sequence CAR T with other treatment options like autologous hematopoietic stem cell transplantation (HSCT) and bispecific antibodies.

Episodes in this series

EP. 1 Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

EP. 1 Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

EP. 2 Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

EP. 2 Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

EP. 3 Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM

EP. 3 Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM

EP. 4 Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

EP. 4 Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

EP. 5 Bridging to CAR T in R/R MM: Best Practices

EP. 5 Bridging to CAR T in R/R MM: Best Practices

EP. 6 Explaining CAR T: Key Points for Patient Counseling

EP. 6 Explaining CAR T: Key Points for Patient Counseling

EP. 7 Overcoming Barriers to CAR T Referral in R/R MM

EP. 7 Overcoming Barriers to CAR T Referral in R/R MM

EP. 8 Collaborative Approach in Managing Post CAR T Care Between Academic and Community Physicians in R/R MM

EP. 8 Collaborative Approach in Managing Post CAR T Care Between Academic and Community Physicians in R/R MM

EP. 9 Clinical Perspectives: Importance of Vaccinations and Infection Prevention Post CAR T, and Monitoring Strategies for Other Potential Late CAR T–Related Toxicities in R/R MM

EP. 9 Clinical Perspectives: Importance of Vaccinations and Infection Prevention Post CAR T, and Monitoring Strategies for Other Potential Late CAR T–Related Toxicities in R/R MM

EP. 10 Exciting Future Horizons for CAR T in MM and Take-Home Messages

EP. 10 Exciting Future Horizons for CAR T in MM and Take-Home Messages

Video content above is prompted by the following:

What is your clinical approach to CAR T-cell therapy in R/R MM? How are you typically sequencing CAR T with the other available treatment options like autologous HSCT and bispecifics?

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