Opinion|Videos|April 7, 2025
Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM
Author(s)Surbhi Sidana, MD, Peter Voorhees, MD
Experts discuss how they decide between utilizing cilta-cel vs ide-cel in multiple myeloma, considering factors like disease characteristics, patient factors, and product differences, while reviewing the final progression-free survival (PFS) analysis from the KarMMA-3 study with ide-cel and key takeaways from the ASH 2024 update on minimal residual disease (MRD) negativity rates from CARTITUDE-4 with cilta-cel and its impact on clinical practice.
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Video content above is prompted by the following:
- How are you deciding between utilizing cilta-cel vs ide-cel, and what factors (disease, patient, and/or product) impact that decision?
- KarMMA-3 with ide-cel also recently reported its final PFS analysis. What were some highlights of this data, and what areyour impressions so far?
- There was a recent update from ASH 2024 regarding the MRD negativity rates from CARTITUDE-4 with cilta-cel; what were some of your key takeaways, and have the data impacted your clinical practice?
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