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Opinion|Videos|April 7, 2025

Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

Author(s)Surbhi Sidana, MD, Peter Voorhees, MD

Experts discuss when physicians should consider referring patients to chimeric antigen receptor (CAR) T-cell therapy for relapsed/refractory multiple myeloma (R/R MM). They emphasize the importance of early referral and access to CAR T in earlier lines of therapy while commenting on the similarities and differences in referral timing, particularly for patients treated in the community.

Episodes in this series

EP. 1 Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

EP. 1 Optimizing CAR T in R/R MM: Treatment Paradigms and Patient Selection

EP. 2 Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

EP. 2 Sequencing CAR T in More Heavily Pretreated R/R MM as well in patients who deferred initial autologous HSCT

EP. 3 Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM

EP. 3 Cilta-cel vs. Ide-cel: Key Data Updates and Clinical Decision-Making in R/R MM

EP. 4 Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

EP. 4 Strategic Timing for CAR T in R/R MM: The Importance of Early Referral

EP. 5 Bridging to CAR T in R/R MM: Best Practices

EP. 5 Bridging to CAR T in R/R MM: Best Practices

EP. 6 Explaining CAR T: Key Points for Patient Counseling

EP. 6 Explaining CAR T: Key Points for Patient Counseling

EP. 7 Overcoming Barriers to CAR T Referral in R/R MM

EP. 7 Overcoming Barriers to CAR T Referral in R/R MM

EP. 8 Collaborative Approach in Managing Post CAR T Care Between Academic and Community Physicians in R/R MM

EP. 8 Collaborative Approach in Managing Post CAR T Care Between Academic and Community Physicians in R/R MM

EP. 9 Clinical Perspectives: Importance of Vaccinations and Infection Prevention Post CAR T, and Monitoring Strategies for Other Potential Late CAR T–Related Toxicities in R/R MM

EP. 9 Clinical Perspectives: Importance of Vaccinations and Infection Prevention Post CAR T, and Monitoring Strategies for Other Potential Late CAR T–Related Toxicities in R/R MM

EP. 10 Exciting Future Horizons for CAR T in MM and Take-Home Messages

EP. 10 Exciting Future Horizons for CAR T in MM and Take-Home Messages

Video content above is prompted by the following:

When should physicians start thinking about referring their patients to CAR T? Why is early referral or allowing access to CAR T in earlier lines of therapy critical for patients with R/R MM?
Please comment on any similarities and/or differences regarding the ideal or most appropriate timing for CAR T referral, especially for those patients treated in the community.

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