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Opinion|Videos|December 29, 2025

The Critical Role of Multidisciplinary Teams in NSCLC

Author(s)Martin Dietrich, MD, PhD, Mark A. Socinski, MD

Experts emphasize the indispensable role of a multidisciplinary team (MDT) in managing non-small cell lung cancer (NSCLC). They highlight that complex cases, like the one discussed, demonstrate how knowledge evolves and how critical collaborative decision-making is for optimal patient outcomes.

Episodes in this series

2 experts are featured in this series

EP. 1 My Treatment Approach: NSCLC Testing and Management of Complex Cases

2 experts are featured in this series

EP. 2 Tissue is Critical: Best Practices for NSCLC Biomarker Testing

2 experts are featured in this series

EP. 3 NSCLC Case Study 1: Staging & Diagnostic Workup for a Lung Nodule

2 experts are featured in this series

EP. 4 NSCLC Case Study 1: Essential Molecular Testing for New Lung Cancer Diagnosis

2 experts are featured in this series

EP. 5 NSCLC Case Study 1: PD-L1 30% and No Mutations

2 experts are featured in this series

EP. 6 Managing Recurrent NSCLC After Immunotherapy & Surgery

2 experts are featured in this series

EP. 7 The Role of DNA & RNA in Comprehensive Genomic Profiling

2 experts are featured in this series

EP. 8 NSCLC Case Study 2: A Never-Smoker with Neuroendocrine Markers

2 experts are featured in this series

EP. 9 NSCLC Cast Study 2: Deciphering Mixed Histology and Negative Biomarkers in NSCLC

2 experts are featured in this series

EP. 10 NSCLC Case Study 2: Navigating Treatment After a RET Fusion Discovery

2 experts are featured in this series

EP. 11 The Diagnostic Challenge of Rare NSCLC Subtypes and Fusions

2 experts are featured in this series

EP. 12 The Critical Role of Multidisciplinary Teams in NSCLC

2 experts are featured in this series

EP. 13 Lymph Node Status & Tumor Size in Lung Cancer Adjuvant Therapy

2 experts are featured in this series

EP. 14 The Future of Lung Cancer: Screening, Treatment & Unmet Needs

Experts emphasize the indispensable role of a multidisciplinary team (MDT) in managing non-small cell lung cancer (NSCLC). They highlight that complex cases, like the one discussed, demonstrate how knowledge evolves and how critical collaborative decision-making is for optimal patient outcomes.

The panel asserts that a tumor board should include not only surgical, medical, and radiation oncologists but also molecular pathologists. This integration is vital for interpreting complex biomarker data, resolving diagnostic discrepancies, and ensuring no patient falls through the cracks. This team-based approach is essential for making nuanced decisions on diagnostic strategies, resectability, and choosing between surgical versus non-surgical management, ultimately guiding personalized and effective treatment plans.

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