When to Initiate Therapy in Myelofibrosis: The Role of Early Intervention

Prithviraj Bose, MD, and Pankit Vachhani, MD, examine considerations surrounding treatment initiation and the potential role of earlier therapeutic intervention in myelofibrosis. Bose discusses risk stratification, symptom burden, and disease trajectory as key factors influencing timing of therapy. Vachhani highlights emerging perspectives that earlier intervention may alter disease course and improve outcomes compared with delayed treatment strategies.