Key Clinical Updates with HER2-Targeting Therapies

EP. 1: Background Information on Targeted Therapies in Breast Cancer
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how the evolution of HER2 testing and classification has redefined treatment strategies and expanded therapeutic opportunities in breast cancer.

EP. 2: Clinical Trial Evidence for HER2-Targeted Therapies in Early Breast Cancer
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how new trial data are optimizing early-stage HER2-positive breast cancer treatment through refined, evidence-based regimens.

EP. 3: The Role of ADCs in Different Subgroups
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how ADCs are revolutionizing HER2-targeted therapy through precision delivery and improved tolerability across patient subgroups.

EP. 4: First-Line Treatment Regimens in Metastatic HER2+ Breast Cancer
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how evolving first-line HER2-targeted combinations are improving outcomes and redefining standards in metastatic breast cancer..

EP. 5: Treatment Sequencing in Later Lines of Therapy in HER2+ Metastatic Breast Cancer
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how thoughtful sequencing of HER2-targeted agents maximizes benefit and extends survival in metastatic settings.

EP. 6: Additional Data with HER2-Targeted Agents in Metastatic Breast Cancer
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how newer HER2-targeted therapies show promise for CNS disease control and broader metastatic management.

EP. 7: Treatment of HER2-Low and Future Therapies in Metastatic Breast Cancer
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how HER2-low and HER3-directed therapies are expanding precision treatment opportunities in metastatic breast cancer.

EP. 8: Disease State Information on TNBC
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how molecular characterization and novel agents are redefining the management of TNBC.

EP. 9: Exciting New Data for TNBC Therapies
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how new trial results from ASCENT-03 and TROPION-Breast02 are shaping next-generation TNBC therapies.

EP. 10: Unmet Needs and Future Outlook for HER2-Targeted Therapies
ByNeil M. Iyengar, MD,Kelly E. McCann, MD, PhD,Kamel Abou Hussein, MD,William J. Gradishar, MD,Sara A. Hurvitz, MD, FACP Panelists discuss how innovative HER2-targeted strategies and precision approaches will define the next era of breast cancer therapy.