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Opinion|Videos|November 1, 2024

Evidence-Based Approaches to Intensive Chemotherapy in Secondary AML

Author(s)Margaret T. Kasner, MD, Christian Fidler, MD

Panelists discuss how the NCCN guidelines recommend intensive chemotherapy options, including traditional 7+3 and CPX-351, for newly diagnosed high-risk or secondary AML patients, with treatment selection based on individual patient factors and potential adverse effects.

Episodes in this series

2 KOLs are featured in this series.

EP. 1 Implementing Updates to AML Classification Guidelines

2 KOLs are featured in this series.

EP. 2 Treatment Goals in Secondary AML

2 KOLs are featured in this series.

EP. 3 The Role of Molecular and Cytogenetic Testing in Secondary AML

2 KOLs are featured in this series.

EP. 4 Patient-Centered Decision-Making in Secondary AML Treatment

2 KOLs are featured in this series.

EP. 5 Assessing Transplant Eligibility and Fitness for Intensive Chemotherapy

2 KOLs are featured in this series.

EP. 6 Evidence-Based Approaches to Intensive Chemotherapy in Secondary AML

2 KOLs are featured in this series.

EP. 7 Navigating Intensive Chemotherapy in the Community Setting

2 KOLs are featured in this series.

EP. 8 Optimizing AML Care Through Academic-Community Collaboration

2 KOLs are featured in this series.

EP. 9 Practice Pearls for Treatment of Secondary AML in the Community Setting

Video content above is prompted by the following:

Please discuss the NCCN guideline recommended first-line treatment options for patients with newly diagnosed high-risk or secondary AML who are potential candidates for intensive chemotherapy induction.
Please briefly review the study design & efficacy study of CPX-351 vs. 7+3.
How do you monitor and manage potential adverse effects in these patients?
- Describe management of both 7+3 and CPX-351.
- How does your approach differ between the two regimens?

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