
Opinion|Videos|January 30, 2026
The Role of Amivantamab Plus Lazertinib in EGFR+ NSCLC
The FDA approval of amivantamab and lazertinib transforms frontline treatment for EGFR-mutated lung cancer, enhancing patient outcomes and convenience.
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Episodes in this series

Joshua K. Sabari, MD, and Alexander I. Spira, MD, PhD, FACP, FASCO, examine the rationale for combining amivantamab with lazertinib in EGFR-mutated NSCLC. They summarize key efficacy signals and how this regimen may compare with existing targeted monotherapy and combination approaches. Clinical considerations for incorporating the combination into practice are also discussed.
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