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Opinion|Videos|February 13, 2026

How Subcutaneous Amivantamab Could Affect Clinical Management of EGFR+ NSCLC

Author(s)Joshua K. Sabari, MD, Alexander I. Spira, MD, PhD, FACP, FASCO

Subcutaneous amivantamab offers significant advantages over IV administration, including reduced infusion reactions and quicker patient turnover in clinics.

Episodes in this series

2 experts are featured in this series.

EP. 1 Current Frontline Treatment Approaches in EGFR+ Advanced NSCLC

2 experts are featured in this series.

EP. 2 The Role of Amivantamab Plus Lazertinib in EGFR+ NSCLC

2 experts are featured in this series.

EP. 3 CNS Metastases in EGFR+ NSCLC: Data for Amivantamab Plus Lazertinib

2 experts are featured in this series.

EP. 4 Safety Considerations for Frontline Regimens in EGFR+ NSCLC

2 experts are featured in this series.

EP. 5 How Subcutaneous Amivantamab Could Affect Clinical Management of EGFR+ NSCLC

2 experts are featured in this series.

EP. 6 Exploring Targeted Strategies in Early-Stage EGFR+ NSCLC

2 experts are featured in this series.

EP. 7 Ongoing Research to Watch in EGFR+ NSCLC

Joshua K. Sabari, MD, and Alexander I. Spira, MD, PhD, FACP, FASCO, discuss the potential impact of a subcutaneous formulation of amivantamab on patient care. They explore how administration route may influence clinic workflow, patient convenience, and treatment experience. Broader implications for access and adherence are also considered.

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