Opinion|Videos|February 20, 2026
Ongoing Research to Watch in EGFR+ NSCLC
Experts discuss the potential of amivantamab and velertinib in early-stage lung cancer treatment, emphasizing the need for careful patient management.
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Episodes in this series
Joshua K. Sabari, MD, and Alexander I. Spira, MD, PhD, FACP, FASCO, highlight emerging agents and trials shaping the future of EGFR-mutated NSCLC care. They discuss novel combinations, resistance-directed strategies, and next-generation targeted therapies. The segment closes with key questions that ongoing research aims to address.
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David VanderWeele, MD, PhD, reviews where lutetium Lu 177 vipivotide tetraxetan fits across metastatic prostate cancer, how to select and manage patients, and the new radionuclides, targeting molecules, and antigens under investigation.
Longer follow-up of CAPItello-281 showed capivasertib plus abiraterone extended survival in PTEN-deficient hormone-sensitive prostate cancer.
Joshua J. Meeks, MD, PhD, explains how enfortumab vedotin plus pembrolizumab is reshaping organ preservation in MIBC.
Katie S. Murray, DO, discusses how efficacy, toxicity, patient preferences, and treatment logistics guide BCG-unresponsive NMIBC care.
Vignesh T. Packiam, MD, reviews why improved BCG outcomes support its first-line use, with gemcitabine/docetaxel as a BCG-sparing option.
Experts break down key gastrointestinal cancer data and trends from the 2026 ESMO Congress.
Experts break down key melanoma data and trends from the 2026 ESMO Congress.
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