Vol. 18/No. 13

Many challenges remain to the optimal interpretation of genetic test results and the effective translation of these data into improved diagnostic, prognostic, and therapeutic capabilities.

The nanotechnology sector has had its share of disappointments in the arena of oncology therapeutics. Nevertheless, the FDA is reviewing a new drug application for a novel compound and numerous investigational agents are in the pipeline.

Investigators are seeking to determine whether the addition of ABT-414 to concomitant radiotherapy and temozolomide will improve the survival of patients with newly diagnosed glioblastoma multiforme with EGFR amplification.

Recent developments in the treatment of metastatic pancreatic cancer have modestly improved outcomes, but reducing morbidities associated with current therapies and developing novel therapeutics will be essential for achieving durable responses and long-term survival.

Research from Tulane University provides a strong case that, across demographic and clinical populations, informed patients are less wary of palliative care and more inclined to take advantage of the favorable effects that palliative care services can offer for patient-centered outcomes.

Studies conducted at VCU Massey Cancer Center in Richmond, Virginia, over the past 7 years have developed the therapeutic combination of pemetrexed and sorafenib (Nexavar) from the bench to the bedside, and now into phase II clinical trial evaluation.

The impact of the Trump administration's agenda is being felt in the healthcare arena, prominently in the oversight for drug approvals.

Joyce A. O'Shaughnessy, MD, whose research helped establish capecitabine and gemcitabine as treatments for patients with breast cancer, was honored in the Community Outreach/Education category with a 2016 Giants of Cancer Care® award, a program that OncLive® developed to recognize leaders in the field.