The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.
FDA Panel Narrowly Supports New CRC Blood Test
March 27th 2014The blood-based colorectal cancer (CRC) screening test Epi proColon passed the scrutiny of the FDA's Molecular and Clinical Genetics advisory panel in a close 5-4 vote with 1 abstention in support of the claim that the test's benefits outweigh its risks
MAGE-A3 Antigen-Specific Vaccine Fails to Extend DFS in NSCLC
March 20th 2014The MAGE-A3-specific immunotherapeutic GSK1572932A failed to significantly extend disease-free survival (DFS) in patients with resected nonmetastatic non-small cell lung cancer (NSCLC) who tested negative for a specific gene expression signature
Nivolumab Delivers Durable Remissions With Low Toxicity in Advanced Melanoma
March 14th 2014Nivolumab, a PD-1-specific antibody, has been shown to produce long-term remissions with limited toxicity in patients with advanced melanoma, according to results from one of the longest follow ups to examine the drug.
Ruxolitinib Improves Outcomes for Patients With Polycythemia Vera in Phase III Study
March 7th 2014Ruxolitinib, a JAK1/2 inhibitor, is the first treatment to demonstrate efficacy in a phase III trial for patients with polycythemia vera (PV), a chronic, incurable blood cancer with limited treatment options
Repealing Sustainable Growth Rate Would Cost $138 Billion Over 10 Years
March 4th 2014Repealing the sustainable growth rate (SGR) formula, a mechanism Congress enacted in 1997 to limit Medicare costs, is going to leave taxpayers with a bill of $60 billion from 2014 through 2019, and a total of $138 billion through 2024.
Highmark Lowers Hospital-Infusion Chemotherapy Rates
February 27th 2014Hospitals and medical centers that provide chemotherapy infusion services to their cancer patients on an outpatient basis generally get paid more than oncologists and hematologists who provide the same services in a private office.