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Opinion|Videos|August 5, 2024

Challenges and Learnings from EVOKE-01

Author(s)Mark A. Socinski, MD, Helena A. Yu, MD, Zosia Piotrowska, MD, MHS

Benjamin Levy, MD, provides an overview of the rationale and study design for the EVOKE-01 trial, which evaluates the efficacy and safety of sacituzumab govitecan in patients with non-small cell lung cancer who have experienced disease progression following treatment with platinum-based chemotherapy and checkpoint inhibitors.

Episodes in this series

5 KOLs are featured in this peer exchange

EP. 1 Treatment Strategies for NSCLC with Non-Actionable Mutations

5 KOLs are featured in this peer exchange

EP. 2 Role of Antibody-Drug Conjugates in NSCLC Treatment: Insights from EVOKE-02

5 KOLs are featured in this peer exchange

EP. 3 Exploring the TROPION-Lung04 Study

5 KOLs are featured in this peer exchange

EP. 4 Exploring Dato-DXd Combinations as First-Line Therapy for Advanced NSCLC

5 KOLs are featured in this peer exchange

EP. 5 Navigating Between ADCs in NSCLC

5 KOLs are featured in this peer exchange

EP. 6 Advancing Treatment for EGFR-Mutant Advanced NSCLC: Lessons from FLAURA2

5 KOLs are featured in this peer exchange

EP. 7 Osimertinib Monotherapy vs. Combination Therapy: Patient Selection in EGFR-Mutant Advanced NSCLC

5 KOLs are featured in this peer exchange

EP. 8 MARIPOSA Study Insights

5 KOLs are featured in this peer exchange

EP. 9 Optimizing Therapy Selection in EGFR Mutant NSCLC

5 KOLs are featured in this peer exchange

EP. 10 ASCO 2024 Updates: Novel Approaches in NSCLC Therapy

5 KOLs are featured in this peer exchange

EP. 11 Overview of TROP2 & Potential Role of TROP2-Directed ADCs in NSCLC

5 KOLs are featured in this peer exchange

EP. 12 Key Takeaways from TROPION Trials: Implications for NSCLC Treatment Landscape

5 KOLs are featured in this series.

EP. 13 Targeting of HER3: Insights from HERTHENA-Lung01

5 KOLs featured in this series

EP. 14 Challenges and Learnings from EVOKE-01

5 KOLs featured in this series

EP. 15 Key ADC Studies at ASCO 2024

5 KOLs featured in this series

EP. 16 Mitigating Toxicities of Dato-DXd, Sacituzumab Govitecan, and HER3-DXd

5 KOLs featured in this series

EP. 17 Patient Selection and Sequencing of NSCLC ADCs

Please review the rationale and study design for EVOKE-01 evaluating sacituzumabgovitecan in patients with NSCLC with disease progression following platinum-based chemotherapy and checkpoint inhibitors. (Garassino, et al. ASCO 2022. Abstract TPS9149)

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