Biosimilars

Julie R. Gralow, MD, discusses the science of biosimilars and their implementation in breast cancer.

Massimo Cristofanilli, MD, discusses the need for biosimilars in oncology.

John M. Pagel, MD, PhD, discusses the use of biosimilars in oncology and the importance of cost consciousness.

John Hays, MD, PhD, discusses the potential for PARP inhibitor combinations in patients with ovarian cancer.

Herbert A. Eradat, MD, discusses the implications of the FDA approval of rituximab-pvvr (Ruxience), a biosimilar to rituximab (Rituxan) in patients with CD20-positive B-cell Non-Hodgkin lymphoma and chronic lymphocytic leukemia.

Ali McBride, PharmD, MS, BCOP, FASHP, FAzPA, discusses the potential utility of biosimilars in oncology.

The trastuzumab biosimilar Ogivri (MYL-1401O; trastuzumab-dkst) has been launched in the United States for all indications of the reference product, including the treatment of patients with HER2-overexpressing breast cancer and metastatic gastric or gastroesophageal junction adenocarcinoma.

The Chinese-manufactured trastuzumab biosimilar HLX02 demonstrated similar objective response rates to the reference product at 24 weeks in patients with treatment-naïve or recurrent metastatic HER2-positive breast cancer.

Lee S. Schwartzberg, MD, FACP, discusses the development and approval process for biosimilars and explains how their availability could drive down out-of-pocket costs for patients.

The FDA has accepted a biologics license application for the proposed bevacizumab biosimilar SB8.

Bradley G. Somer, MD, discusses the emergence of biosimilars in oncology

The slate of biosimilars for cancer is growing, and with this expansion the potential for price competition has improved.

Erika P. Hamilton, MD, discusses the impact of biosimilars in oncology.

Jim M. Koeller, MS FHOPA, discusses the heterogeneity of biologics.

Bradley G. Somer, MD, discusses lowering the cost of cancer care with biosimilars.

Kurt Tauer, MD, FACP, discusses arguments in favor of and against biosimilars in oncology.

Komal Jhaveri, MD, FACP, discusses the use of trastuzumab biosimilars in breast cancer.

Lee S. Schwartzberg, MD, FACP, chief medical officer, OneOncology, chief and professor of medicine, Division of Hematology/Oncology, the University of Tennessee Health Science Center, medical director, West Clinic, and executive director, West Cancer Center, discusses the use of therapeutic biosimilars in breast cancer.

The FDA has approved the pegfilgrastim biosimilar LA-EP2006 (pegfilgrastim-bmez; Ziextenzo) as a treatment to decrease the incidence of infection, exhibited from febrile neutropenia, in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer therapy that is associated with a clinically significant incidence of febrile neutropenia.

Gregory Vidal, MD, PhD, explains how biosimilars could increase access to HER2-targeted therapy.

Anthony R. Mato, MD, MSCE, discusses the introduction of rituximab biosimilars in chronic lymphocytic leukemia.

Jacopo Giuliani, MD, discusses the analysis of the economic impact of biosimilars in breast cancer and follicular lymphoma.

Mark E. Robson, MD, chief, Breast Medicine Service, Memorial Sloan Kettering Cancer Center, discusses the driving force behind biosimilar use in oncology.

Scott Gottlieb, MD, discusses facets of biosimilar development as well as commercial and policy changes that could have the greatest impact on the use of these products in the field of oncology.

Manish A. Shah, MD, discusses the use of trastuzumab biosimilars in gastric cancer.