Lung Cancer | Specialty

The OncLive Lung Cancer condition center page is a comprehensive resource for clinical news and expert insights on non–small cell lung cancer, small cell lung cancer, mesothelioma, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in lung cancer.

Dr. Camidge on Toxicities of Sunvozertinib in EGFR Exon 20–Mutated NSCLC

October 20th 2022

Ross Camidge, MD, PhD, discusses toxicities observed with sunvozertinib in EGFR exon 20–mutated non–small cell lung cancer.

Updates in The Treatment of Advanced NSCLC with Immune Checkpoint Inhibitors

October 19th 2022

Drs Peters and Johnson discuss recent updates in the treatment of advanced NSCLC with single- and dual-agent immunotherapy regimens.

Multidisciplinary Therapy and Molecular Testing in Early-Stage NSCLC

October 19th 2022

Dr Melissa Johnson and Dr Myung-Ju Ahn emphasize the importance of a multidisciplinary approach to treatment and biomarker testing for patients with early-stage NSCLC.

Selecting Appropriate Patients with NSCLC for Neoadjuvant Therapy

October 19th 2022

Joshua Sabari, MD, describes which stage groups of patients with NSCLC should receive neoadjuvant therapies, and which therapies are typically used.

The Role of Neoadjuvant Therapy in Patients with Resectable NSCLC

October 19th 2022

Drs Wakelee, Sabari, and Wistuba review updated data on neoadjuvant treatment in NSCLC from key studies including CheckMate-816 and NADIM-2.

Average Turnaround Time for NSCLC Molecular Testing

October 19th 2022

Dr Neil Morganstein explains the typical turnaround times for molecular testing he sees and the challenges that prolong the process.

Best Practices for Accurate Tissue Genotyping in NSCLC

October 19th 2022

Dr Bhuvana Ramkumar shares best practices for molecular testing in NSCLC to obtain the most accurate results.

Novel HER2-Targeted Therapies for NSCLC

October 17th 2022

Closing out their discussion, the panel highlights investigational therapies in NSCLC to look out for.

Challenges and Unmet Needs in HER2-Mutated or Amplified NSCLC

October 17th 2022

The panel discusses the challenges of treatment and unmet needs of HER2-mutated or amplified NSCLC.

Community Perspectives on Integrating and Interpreting Molecular Testing Results in NSCLC

October 17th 2022

Drs Ramkumar and Morganstein discuss the challenges they face with integrating and organizing molecular testing results into electronic medical records, how they address non–small cell lung cancer test results with patients, and their hopes for the future of pathology at their institutions.

Unmet Needs in NSCLC Therapy

October 17th 2022

Drs Anil Vachani and Mark Socinski continue their discussion of anti-HER2 therapies by mentioning some of the unmet needs in NSCLC treatment despite the range of available treatment options.

Dr. Iams on Small Cell Lung Cancer Subtyping in Clinical Practice

October 17th 2022

Wade T. Iams, MD, discusses the potential for providing small cell lung cancer subtyping in clinical practice.

The Role of Adjuvant Immunotherapy in the Treatment of Resectable NSCLC

October 17th 2022

Vamsidhar Velcheti, MD, summarizes recent data on adjuvant immunotherapy treatment in resectable NSCLC.

Neoadjuvant and Adjuvant Immunotherapy in Resectable NSCLC: The NEOCoast Trial

October 17th 2022

Dr Myung-Ju Ahn describes the unique design and outcomes of the NEOCoast study that is evaluating immunotherapy regimens in the neoadjuvant and adjuvant settings.

Updates in the Treatment of Stage I-IIIA NSCLC

October 17th 2022

The panel reviews updates in the treatment of stage I-IIIA NSCLC and discusses its impact in clinical practice.

Is There a Role for Liquid Biopsies in Early NSCLC?

October 17th 2022

Ignacio Wistuba, MD, leads the discussion on the role of liquid biopsies for molecular testing in early NSCLC.

Is Therapeutic Value a New Name for Medical Paternalism?

October 14th 2022

What is noteworthy is the process whereby this patient employs both objective data and his personal beliefs to declare what he values.

FDA Approval Insights: Selpercatinib in RET Fusion–Positive Solid Tumors

October 13th 2022

Dr Subbiah discusses the significance of the FDA approval of selpercatinib in RET fusion–positive non–small cell lung cancer, thyroid cancer, and other solid tumors.

Sotorasib/BBP-398 Combo Snags FDA Fast Track Status for KRAS G12C–Mutated NSCLC

October 12th 2022

A combination regimen comprised of sotorasib and BBP-398 has been awarded a fast track designation from the FDA for use as a potential therapeutic option in adult patients with previously treated, KRAS G12C–mutated, metastatic non–small cell lung cancer.

Avelumab and Axitinib Elicits Responses in Advanced Thymoma and Thymic Carcinoma

October 12th 2022

The combination of avelumab and axitinib demonstrated promising response rates and progression-free survival and an expected safety profile in pretreated patients with advanced type B3 thymoma and thymic carcinoma, according to findings from an ongoing phase 2 study.