NCCN Guidelines Include an Abundance of Options Across Multiple Myeloma Paradigm
March 30th 2021The National Comprehensive Cancer Network guidelines for the management of frontline and relapsed/refractory multiple myeloma were updated to incorporate novel agents and combination strategies, providing a wide range of category 1 recommended therapies for patients.
Northfelt Navigates Advances Made to Improve iDFS, Reduce Relapse Risk in ER+ Breast Cancer
March 24th 2021Donald W. Northfelt, MD, MS, FACP, discusses the progress made with CDK4/6 inhibitors in the treatment of patients with ER-expressing breast cancer and pivotal trials that have moved the needle forward.
Personalized Radioembolization Improves OS Vs Standard Dosing in Advanced HCC
March 1st 2021Yttrium-90 glass microspheres administered in a personalized, dosimetric approach demonstrated a 16-month improvement in overall survival compared with a standard dosimetric approach in patients with unresectable hepatocellular carcinoma.
Targeted Therapies Dominate the Relapsed/Refractory CLL Paradigm
February 27th 2021Targeted therapies have helped to improve responses in patients with relapsed chronic lymphocytic leukemia regardless of high-risk disease, although optimal sequencing and toxicity management need to be further explored to strengthen the utilization of these options.
T-Cell Engagers and Combinations Push Myeloma Paradigm Forward
February 10th 2021Sikander Ailawadhi, MD, discusses the future of relapsed/refractory multiple myeloma, the potential for retreatment with proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies, and the promise of T-cell engagers in the field.