The OncLive Pediatric Oncology condition center page is a comprehensive resource for clinical news and expert insights on various types of cancers in pediatric patients, including acute lymphoblastic leukemia, acute myeloid leukemia, brain cancers, sarcomas, and more. This page features news articles, interviews in written and video format, and podcasts that focus on unmet needs, treatment advances, and ongoing research in childhood and adolescent and young adult cancers.
April 10th 2025
The FDA has granted full approval to larotrectinib for select patients with solid tumors harboring a NTRK gene fusion.
Coffee Talk™: Navigating the Impact of HER2/3, TROP2, and PARP from Early Stage to Advanced Breast Cancer Care
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Go To PER in Chicago
May 30, 2025 - June 3, 2025
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Fighting Disparities and Saving Lives: An Exploration of Challenges and Solutions in Cancer Care
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Epithelioid Sarcoma: Applying Clinical Updates to Real Patient Cases
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Collaborating Across the Continuum®: Identifying and Treating Epithelioid Sarcoma
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Mastering Epithelioid Sarcoma: Enhancing Diagnostic Precision and Tailoring Treatment Strategies
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Clinical Showcase™: Selecting the Best Next Steps for a Patient with Epithelioid Sarcoma
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Annual Hawaii Cancer Conference
January 24-25, 2026
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FDA Approval Sought for Blinatumomab in Pediatric Acute Lymphoblastic Leukemia
March 3rd 2016A supplemental biologics license application has been submitted to the FDA to expand the approval of blinatumomab (Blincyto) to include the treatment of pediatric and adolescent patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia.
Dr. Stephen Grupp on Engineered Cell Therapy for the Treatment of Pediatric ALL
November 5th 2015Stephen Grupp, MD, PhD, director of translational research for the center for Childhood Cancer Research at The Children's Hospital of Philadelphia (CHOP) and medical director of the Stem Cell Laboratory at CHOP, discusses the use of engineered cell therapy for the treatment of Acute Lymphoblastic Leukemia (ALL).
Intensified Chemotherapy Extends EFS for Children With Wilms Tumor
Treatment with an intensified chemotherapy regimen was associated with improvements in event-free survival for children with favorable histology Wilms tumor with loss of heterozygosity in chromosomes 1p and 16q.
Eribulin Shows Promise in Pediatric Sarcomas
Eribulin has demonstrated a high level of antitumor activity that was equivalent or superior to vincristine across several sarcoma xenograft models, including at low dose levels, suggesting the drug may effectively treat pediatric patients with sarcoma.